ELA2 Pre-design Chimera RNAi-RNAi技术-试剂-生物在线
亚诺法生技股份有限公司(Abnova)
ELA2 Pre-design Chimera RNAi

ELA2 Pre-design Chimera RNAi

商家询价

产品名称: ELA2 Pre-design Chimera RNAi

英文名称: ELA2 Pre-design Chimera RNAi

产品编号: H00001991-R01

产品价格: 0

产品产地: 台湾

品牌商标: Abnova

更新时间: null

使用范围: null

亚诺法生技股份有限公司(Abnova)
  • 联系人 :
  • 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
  • 邮编 : 11493
  • 所在区域 : 台湾
  • 电话 : +886-920**1152 点击查看
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  • 邮箱 : sales@abnova.com.tw

  • Specification
  • Product Description:
  • Homo sapiens elastase 2, neutrophil (ELA2), mRNA.
  • Reactivity:
  • Human
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_001972
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 1991
  • Gene Name:
  • ELA2
  • Gene Alias:
  • GE,HLE,HNE,NE,PMN-E
  • Gene Description:
  • elastase 2, neutrophil
  • Gene Summary:
  • Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins. The product of this gene hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix following the protein's release from activated neutrophils. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is clustered with other serine protease gene family members, azurocidin 1 and proteinase 3 genes, at chromosome 19pter. All 3 genes are expressed coordinately and their protein products are packaged together into azurophil granules during neutrophil differentiation. [provided by RefSeq
  • Other Designations:
  • bone marrow serine protease,granulocyte-derived elastase,leukocyte elastase,medullasin,polymorphonuclear elastase

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