ADRB2 polyclonal antibody-抗体-抗体-生物在线

产品名称： ADRB2 polyclonal antibody

英文名称： ADRB2 polyclonal antibody

产品编号： PAB2837

产品价格： null

产品产地：台湾

品牌商标： Abnova

更新时间： null

使用范围：

亚诺法生技股份有限公司（Abnova)

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Immunogen:
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human ADRB2.

Storage Instruction:
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Recommend Usage:
ELISA (1:1000)
Western Blot (1:100-500)
Immunohistochemistry (Not Tested)
The optimal working dilution should be determined by the end user.

Note:
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

1.
Association between a beta2-adrenergic receptor polymorphism and elite endurance performance.
Wolfarth B, Rankinen T, Muhlbauer S, Scherr J, Boulay MR, Perusse L, Rauramaa R, Bouchard C.Metabolism. 2007 Dec;56(12):1649-51.

2.
High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.
Cherezov V, Rosenbaum DM, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Kuhn P, Weis WI, Kobilka BK, Stevens RC.Science. 2007 Nov 23;318(5854):1258-65. Epub 2007 Oct 25.

Western Blot (Cell lysate)
Western blot analysis of ADRB2 polyclonal antibody (Cat # PAB2837) in HL-60 cell line lysates (35 ug/lane). ADRB2 (arrow) was detected using the purified polyclonal antibody (1 : 440 dilution).

Gene Summary:
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq