HTATIP polyclonal antibody
产品名称： HTATIP polyclonal antibody
英文名称： HTATIP polyclonal antibody
产品编号： PAB2247
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of HTATIP.
- Immunogen:
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human HTATIP.
- Host:
- Rabbit
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Protein G purification
- Storage Buffer:
- In PBS (0.09% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:1000)
Western Blot (1:100-500)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes.
Cai Y, Jin J, Florens L, Swanson SK, Kusch T, Li B, Workman JL, Washburn MP, Conaway RC, Conaway JW.J Biol Chem. 2005 Apr 8;280(14):13665-70. Epub 2005 Jan 11.
- 2.
- The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60.
Patel JH, Du Y, Ard PG, Phillips C, Carella B, Chen CJ, Rakowski C, Chatterjee C, Lieberman PM, Lane WS, Blobel GA, McMahon SB.Mol Cell Biol. 2004 Dec;24(24):10826-34.
- 3.
- Role of the histone acetyl transferase Tip60 in the p53 pathway.
Legube G, Linares LK, Tyteca S, Caron C, Scheffner M, Chevillard-Briet M, Trouche D.J Biol Chem. 2004 Oct 22;279(43):44825-33. Epub 2004 Aug 13.
- Entrez GeneID:
- 10524
- Protein Accession#:
- NP_006379;Q92993
- Gene Name:
- KAT5
- Gene Alias:
- ESA1,HTATIP,HTATIP1,PLIP,TIP,TIP60,cPLA2
- Gene Description:
- K(lysine) acetyltransferase 5
- Omim ID:
- 601409
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq
- Other Designations:
- HIV-1 Tat interactive protein, 60kDa,K-acetyltransferase 5,Tat interacting protein, 60kDa,cPLA2 interacting protein