CBX3 monoclonal antibody (M01), clone 1G12-1D9
产品名称： CBX3 monoclonal antibody (M01), clone 1G12-1D9
英文名称： CBX3 monoclonal antibody (M01), clone 1G12-1D9
产品编号： H00011335-M01
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a full length recombinant CBX3.
- Immunogen:
- CBX3 (AAH00954, 1 a.a. ~ 183 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- MASNKTTLQKMGKKQNGKSKKVEEAEPEEFVVEKVLDRRVVNGKVEYFLKWKGFTDADNTWEPEENLDCPELIEAFLNSQKAGKEKDGTKRKSLSDSESDDSKSKKKRDAADKPRGFARGLDPERIIGATDSSGELMLLMKWKDSDEADLVLAKEANMKCPQIVIAFYEERLTWHSCPEDEAQ
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a kappa
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (45.87 KDa) .
- MSDS:
Download
- Publication Reference
- 1.
- Loss of the candidate tumor suppressor BTG3 triggers acute cellular senescence via the ERK-JMJD3-p16(INK4a) signaling axis.
Lin TY, Cheng YC, Yang HC, Lin WC, Wang CC, Lai PL, Shieh SY.Oncogene. 2011 Oct 24. doi: 10.1038/onc.2011.491.
- Applications
- Western Blot (Cell lysate)
- CBX3 monoclonal antibody (M01), clone 1G12-1D9 Western Blot analysis of CBX3 expression in HeLa ( Cat # L013V1 ).
- Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Immunofluorescence
enlarge this image- Immunofluorescence of monoclonal antibody to CBX3 on HeLa cell. [antibody concentration 10 ug/ml]
- Protocol Download
- Sandwich ELISA (Recombinant protein)
- Detection limit for recombinant GST tagged CBX3 is approximately 0.03ng/ml as a capture antibody.
- Protocol Download
- Entrez GeneID:
- 11335
- GeneBank Accession#:
- BC000954
- Protein Accession#:
- AAH00954
- Gene Name:
- CBX3
- Gene Alias:
- HECH,HP1-GAMMA,HP1Hs-gamma
- Gene Description:
- chromobox homolog 3 (HP1 gamma homolog, Drosophila)
- Omim ID:
- 604477
- Gene Ontology:
- Hyperlink
- Gene Summary:
- At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene. [provided by RefSeq
- Other Designations:
- HP1 gamma homolog,OTTHUMP00000024529,OTTHUMP00000122519,chromobox homolog 3,heterochromatin protein HP1 gamma,heterochromatin-like protein 1